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Endocrine Abstracts

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ea0038ja3 | Society for Endocrinology Journal Award ‐ <emphasis role="italic">Endocrine-Related Cancer</emphasis> | SFEBES2015

Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad

Haller Florian , Moskalev Evgeny A , Faucz Fabio R , Barthelmesz Sarah , Wiemann Stefan , Bieg Matthias , Assie Guillaume , Bertherat Jerome , Schaefer Inga-Marie , Otto Claudia , Rattenberry Eleanor , Maher Eamonn R , Strobel Philipp , Werner Martin , Carney J Aidan , Hartmann Arndt , Stratakis Constantine A , Agaimyg Abbas

Endocrine-Related Cancer 2014 21 567–577. DOI: 10.1530/ERC-14-0254...
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ea0031oc5.8 | Pituitary and neoplasia | SFEBES2013

Pituitary adenoma and phaeochromocytoma/paraganglioma – a novel syndrome with a heterogeneous genetic background

Denes Judit , Swords Francesca , Rattenberry Eleanor , Xekouki Paraskevi , Kumar Ajith , Wassif Christopher , Fersht Naomi , Baldeweg Stephanie , Morris Damian , Lightman Stafford , Thompson Chris J , Agha Amar , Rees Aled , Druce Maralyn , Grieve Joan , Powell Michael , Boguszewski Cesar Luiz , Higham Claire , Davis Julian , Preda Cristina , Trouillas Jacqueline , Dalantaeva Nadezhda , Ribeiro-Oliveira Antonio , Dutta Pinaki , Roncaroli Federico , Thakker Rajesh V , Stevenson Mark , O'Sullivan Brendan , Taniere Phillipe , Skordilis Kassiani , Gabrovska Plamena , Barlier Anne , Ellard Sian , Stals Karen , Stratakis Constantine A. , Grossman Ashley B. , Maher Eamonn , Korbonits Marta

Pituitary adenomas and phaeochromocytoma/paragangliomas (PHAEO/PGL) can very rarely occur in the same patient or in the same family. Together, they are not known to be part of any classical endocrine neoplasia syndromes. In some caes the pathogenetic mechanism may be secondary to a PHAEO secreting GHRH leading to somatotroph hyperplasia and clinical acromegaly. However, we suggest several other mechanisms which could lead to the development of pituitary and PHAEO/PGL together:...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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